Gene interactions and pathways from curated databases and text-mining

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CASP1 — SERPINB9

Text-mined interactions from Literome

Kannan-Thulasiraman et al., J Biol Chem 2002 : Proteinase inhibitor 9 (PI-9) inhibits caspase-1 ( interleukin (IL)-1beta converting enzyme ) and granzyme B, thereby regulating production of the pro-inflammatory cytokine IL-1beta and susceptibility to granzyme B-induced apoptosis
Boileau et al., Arthritis Rheum 2002 (Osteoarthritis) : At 12 weeks after surgery, cartilage from the femoral condyles and tibial plateaus were processed for immunohistochemistry for ICE, IL-18, and protease inhibitor 9 (PI-9) , a natural inhibitor of ICE , followed by morphometric analysis
Toossi et al., J Infect Dis 2012 : Inhibition of PI-9 by small inhibitory RNA decreased M. tuberculosis induced expression of the antiapoptotic molecule Bcl-2 and resulted in a corresponding increase in production of caspase 3, a terminal effector molecule of apoptosis