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CD28 — IL8
Text-mined interactions from Literome
Okkenhaug et al., Nat Immunol 2001
:
Nonetheless, this mutated form of
CD28 still prevents the induction of anergy and
promotes T cell proliferation,
interleukin 2 secretion and B cell help
Shapiro et al., Blood 2001
(Disease Progression...) :
Furthermore, stimulation of endogenous
CD28 expressed by 3 myeloma cell lines
increased IL-8 production
Marin et al., Exp Hematol 2007
(Precursor Cell Lymphoblastic Leukemia-Lymphoma) :
Moreover, the presence of 4-1BB or
CD28 in the receptor
increased the production of interleukin (IL)-2, tumor necrosis factor (TNF)-alpha, TNF-beta, IL-5, IL-6, and
IL-8 elicited by coculture with ALL cells
Abreu et al., Arthritis Res Ther 2010
(Arthritis, Experimental...) :
Ex vivo, Rac1 inhibitory peptide suppressed T-cell
receptor/CD28 dependent production of tumor necrosis factor alpha, interferon gamma and
interleukin-17 by T cells from collagen primed mice, and reduced induction of ICOS and CD154, T-cell costimulatory proteins important for B-cell help
Dagur et al., J Autoimmun 2011
(Autoimmune Diseases...) :
Upon TCR
stimulation with
CD3/CD28 , CD4 ( + ) CD146 ( + ) T cells secrete significantly more IL-17A, IL-6, and
IL-8 than do CD4 ( + ) CD146 ( - ) T cells