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APOB — PON1

Text-mined interactions from Literome

Mackness et al., Biochem Biophys Res Commun 2004 : Human HDL and PON1 significantly inhibited the in vitro oxidation of LDL and completely prevented the ox-LDL induced increase in MCP-1 production by endothelial cells ... PON1 attenuates the ox-LDL induced MCP-1 production by endothelial cells
Kabaroglu et al., Acta Cardiol 2004 (Acute Disease...) : High-density lipoprotein ( HDL ) -associated paraoxonase ( PON1 ) was shown to inhibit LDL and HDL oxidation
He et al., Chin Med J (Engl) 2006 (Alzheimer Disease) : Paraoxonase 1 (PON1) , an enzyme located on high-density lipoprotein, can prevent LDL from oxidation to some extent
Kovács et al., J Nephrol 2006 (Disease Progression...) : HDL associated paraoxonase ( PON1 ) reduces oxidation of lipids in LDL , and activity is inversely related to coronary heart disease risk with a beneficial effect on the development of atherosclerosis
Abdin et al., J Diabetes Complications 2010 (Diabetes Mellitus, Type 2...) : The obtained results showed that PON1 activity and HDL significantly decreased and fasting glucose significantly increased in Group I and Group II when compared to the control group, with significant difference in their levels between Group II and Group I. MDA, total cholesterol, and LDL levels significantly increased and glutathione reductase activity significantly decreased in Group I and Group II when compared to the control group
Vakili et al., Adv Exp Med Biol 2010 (Atherosclerosis...) : Several lines of evidence indicate that serum paraoxonase 1 (PON1) acts as an important guardian against cellular damage from oxidized lipids in plasma membrane, in low-density lipoprotein (LDL) , against bacterial endotoxin and against toxic agents such as pesticide residues including organophosphates