Zayed et al., Arthritis Res Ther 2008
(Osteoarthritis...) :
Specific inhibitors of the MAPK p38 ( SB 203580 ) and c-jun N-terminal kinase ( JNK ) ( SP600125 ) and of the NF-kappaB ( SN-50 ) and Notch ( DAPT ) signalling pathways suppressed IL-1beta induced upregulation of L-PGDS expression
Black et al., Biochem Pharmacol 2011
:
Inhibition of p38 blocked UVB induced expression of TNFa, COX-2, PGDS and 15-LOX-2, while JNK inhibition suppressed TNFa and HO-1