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GRAP2 — TAB1

Text-mined interactions from Literome

Cheung et al., EMBO J 2003 : Our results suggest that TAB1 participates in a SAPK2a/p38alpha mediated feedback control of TAK1 , which not only limits the activation of SAPK2a/p38alpha but synchronizes its activity with other signalling pathways that lie downstream of TAK1 ( JNK and IKK )
Makeeva et al., Endocrinology 2008 : Cytokine ( IL-1beta + interferon-gamma ) -stimulated p38 phosphorylation was significantly increased by TAB1alpha overexpression, but not TAB1beta overexpression, in beta-TC6 cells
Tang et al., J Exp Med 2008 (Bone Marrow Diseases...) : Activation of TAK1 by proinflammatory cytokines and T and B cell receptors induces the nuclear localization of nuclear factor kappaB (NF-kappaB) and the activation of c-Jun N-terminal kinase (JNK)/AP1 and P38 , which play important roles in mediating inflammation, immune responses, T and B cell activation, and epithelial cell survival
Shin et al., Biochim Biophys Acta 2009 : Collectively, these results demonstrated that EGFR activation interfered with TNF-alpha induced TAK1 activation via p38 mediated phosphorylation of TAB1