Kaliński et al., J Immunol 2000
:
However, in contrast to IFN-gamma, IL-4 inhibits the CD40 ligand induced production of inactive IL-12p40 and the production of either form of IL-12 induced by LPS, which may explain the view of IL-4 as an IL-12 inhibitor
Cattaruzza et al., J Biol Chem 2003
:
Moreover, CD154 induced IL-12 p40 expression is enhanced after blockade of NOS-3 activity but attenuated in the presence of exogenous nitric oxide
Feder-Mengus et al., Hum Gene Ther 2005
(Neoplasms) :
Most importantly, IL-12 p40 gene expression and protein secretion were induced by CD154rVV but not by wild-type VV ( WT VV ) in either CD14+ cells or iDC, and these effects could be blocked by anti-CD40 monoclonal antibodies