Gene interactions and pathways from curated databases and text-mining

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IL10 — TNFSF11

Text-mined interactions from Literome

Park et al., Exp Mol Med 2005 : In addition, RANKL increased the expression of TNFalpha, MCP-1, and IL-6 but not of IL-10 , IL-12, IFN-gamma, and iNOS
Liu et al., Eur J Oral Sci 2006 (Alveolar Bone Loss) : Interleukin-10 enhanced the expression of OPG and down-regulated the expression of RANKL and CSF-1
Ernst et al., Clin Exp Immunol 2007 (Bone Resorption...) : Finally, IL-10 suppressed both soluble RANKL ( sRANKL ) and membrane RANKL ( mRANKL ) expression by peripheral blood mononuclear cells ( PBMC ) activated in vitro in a bacterial antigen-specific manner
Zheng et al., Biochem Pharmacol 2013 (Bone Resorption) : Coumermycin A1 also abrogated RANKL induced expression of interleukin-1ß , tumor necrosis factor-a, and inducible nitric oxide synthase in mouse BMMs. Consistent with the in vitro anti-osteoclastogenic effect, the aminocoumarin suppressed lipopolysaccharide induced osteoclast formation and bone loss in in vivo mouse experiments