Gene interactions and pathways from curated databases and text-mining

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CDK5 — PARP1

Text-mined interactions from Literome

Korhonen et al., Neurosci Lett 2005 (Nerve Degeneration) : MK-801 ( NMDA receptor antagonist ) as well as benzamide ( PARP inhibitor ), MDL 28170 ( calpain inhibitor ) and roscovitine ( cyclin dependent kinase inhibitor ) inhibited the glutamate response to the YY1 complexes
Bolin et al., Cell Mol Life Sci 2012 : We hypothesize that Cdk5 dependent PARP-1 phosphorylation on one or more of these serines results in an attenuation of its ribosylating activity facilitating persistence at DNA damage sites
Utreras et al., Neurochem Int 2013 : Cdk5 regulates Rap1 activity