◀ Back to IFNG

IFNG — PDCD1LG2

Text-mined interactions from Literome

Yamazaki et al., J Immunol 2002 (Leukemia L5178...) : In contrast, B7-DC expression was only inducible on macrophages and DCs upon stimulation with IFN-gamma , GM-CSF, or IL-4
He et al., Cancer Immunol Immunother 2005 (Adenocarcinoma...) : Low level of IFN-gamma upregulates expression of PD-L1, PD-L2 , CTLA-4 and Foxp3, which may partly account for the tumor immune evasion promoted by IFN-gamma
Tsuda et al., Biochem Biophys Res Commun 2005 : B7-H1 and B7-DC were also upregulated by stimulation with IFN-gamma , IL-13, and the supernatant from T cell clones
Chen et al., Int Immunopharmacol 2005 : Moreover, the significant damping effect of sinomenine on B7-H1 and B7-DC signals could promote IL-2 and IFN-gamma production by co-cultured CD4 ( + ) T cell
Kim et al., Am J Respir Cell Mol Biol 2005 : Expression of B7-H1 and B7-DC was selectively induced by stimulation of either BEAS2B or primary nasal epithelial cells ( PNEC ) with interferon (IFN)-gamma ( 100 ng/ml )
Saunders et al., Eur J Immunol 2005 : In this study, we demonstrate that on human T cells, PD-L2 acts only as a negative regulator of T cell activity, inhibiting proliferation, IL-2 production, and IFN-gamma production via its interaction with programmed death-1 (PD-1)
Wu et al., Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2008 (Hepatitis B) : Whether or not transinfected with HBV, IFN-alpha and IFN-gamma both can induce the liver cell lines ( HepG2 cells and HepG2.2.15 cells ) PD-L1 expression while IL-4 can not ; IL-4, IFN-alpha, IFN-gamma all can induce the PD-L2 expression in HepG2.2.15 cells which was transinfected with HBV, only IFN-gamma can induce the PD-L2 expression in HepG2 cells which was not transinfected with HBV ... IFN-alpha, IFN-gamma both can induce the PD-L1 expression in HepG2 cells and HepG2.2.15 cells, while it is easy for cytokines to induce the PD-L2 expression in HepG2.2.15 cells which was transinfected with HBV, this may provide a potential mechanism of the molecular basis for chronic HBV infection
Nagamatsu et al., Hum Reprod 2009 : B7-H1 blockade on DSCs strongly enhanced T cell cytokine production ( IFN-gamma , TNF-alpha and IL-2 ), whereas B7-DC blockade had similar but more modest effects
Deng et al., J Cancer Res Clin Oncol 2011 (Neoplasms) : Interferon gamma ( IFN-? ) can induce B7-DC expression on macrophages and has been shown to regulate anti-tumor immunity by various mechanisms