Yang et al., Mol Cell 2006
(MAP Kinase Signaling System) :
While PIASxalpha functions as a coactivator to facilitate SUMO and HDAC-2 removal from Elk-1 in response to ERK pathway activation, PIASxalpha acts in the opposite manner to inhibit HDAC-2 and SUMO loss following stress activated MAP kinase pathway signaling
Whitmarsh et al., Mol Cell Biol 1997
:
In contrast, SAP-1 is activated by ERK and p38 MAP kinases but not by JNK