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PIK3CG — XRCC6
Text-mined interactions from Literome
Canobbio et al., Blood 2009
:
However, PI3Kbeta, but not
PI3Kgamma , enzymatic activity was absolutely
required for Akt phosphorylation,
Rap1 activation, and platelet aggregation downstream of the immunoreceptor tyrosine based activation motif ( ITAM ) -bearing receptor glycoprotein VI (GPVI)
Gilio et al., J Biol Chem 2009
(Thrombosis) :
Furthermore, PI3Kalpha/beta, but not
PI3Kgamma ,
contributed to GPVI induced
Rap1b activation and, surprisingly, also to Rap1b independent platelet activation via GPVI