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EPHB2 — MAP3K13
Text-mined interactions from Literome
Bloem et al., J Mol Cell Cardiol 2001
(Cardiomegaly...) :
When expressed in cardiac myocytes,
MLK7 activated SAPK/JNK1, and
ERK and p38 to a lesser extent
Chadee et al., Proc Natl Acad Sci U S A 2006
:
Thus,
MLK3 is part of a multiprotein complex and is
required for
ERK activation
Kovalenko et al., Am J Physiol Gastrointest Liver Physiol 2012
(Intestinal Diseases...) :
MLK inhibition
reduced ERK and JNK, but not p38, signaling in Caco-2 cells
Hebron et al., Br J Haematol 2013
(Multiple Myeloma...) :
In myeloma tumour cells,
MAP3K8 acts as mitogen induced MAP3K in mitosis and is
required for TNFa mediated
ERK activation