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IRF6 — THBD
Text-mined interactions from Literome
Kume et al., J Hepatol 2003
(Liver Diseases...) :
To elucidate the mechanism of liver dysfunction occurring in patients with sepsis, we evaluated the
effect of bacterial
lipopolysaccharide (LPS) on the expression of
thrombomodulin (TM) in rat sinusoidal endothelial cells ( SECs ) and the therapeutic efficacy of exogenous recombinant TM
Verbon et al., J Infect Dis 2003
(Endotoxemia) :
Furthermore,
LPS reduced thrombin-activatable fibrinolysis-inhibitor antigen levels and
increased soluble
thrombomodulin levels, which were not influenced by IC14
Gao et al., J Nat Med 2009
(Sepsis) :
In vitro, SAM reversed the decreased expressions of
thrombomodulin (TM) and endothelial PC receptor ( EPCR ) mRNA
induced by
lipopolysaccharide (LPS) in endothelial cells
Herbert et al., FEBS Lett 1993
:
When measured in parallel, IL-4 and IL-13 counteracted
thrombomodulin down-regulation
induced by
LPS , IL-1 or TNF in endothelial cells