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CA8 — CASP9
Text-mined interactions from Literome
Lu et al., Lung Cancer 2004
(Adenocarcinoma...) :
Interestingly, ectopic
CA-RP VIII expression markedly
reduced caspase-3 activity induced by serum starvation and anti-cancer agents in PC-9 cells
Van Geelen et al., Drug Resist Updat 2004
(Colorectal Neoplasms) :
Additional intracellular factors leading to TRAIL-resistance affect the caspase 8/c-FLIP ratio, such as loss of caspase 8 and caspase 10 due to mutations or gene methylation,
CARP dependent degradation of active caspase 8 and changes in
caspase 8 or c-FLIP expression levels