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MAPK8 — SOD3
Text-mined interactions from Literome
Dai et al., Mol Cell Biol 2005
(Leukemia) :
Inhibition of NF-kappaB by pharmacological inhibitors or genetic strategies markedly potentiated apoptosis induced by HDACIs, and this was accompanied by enhanced reactive oxygen species ( ROS ) generation, downregulation of
Mn-superoxide dismutase and XIAP, and
c-Jun N-terminal kinase 1 ( JNK1 )
activation
Nito et al., J Cereb Blood Flow Metab 2008
(Brain Edema...) :
Moreover, overexpression of
copper/zinc-superoxide dismutase remarkably
diminished activation and phosphorylation of both p38
MAPK and cPLA(2) after reperfusion
Gaitanaki et al., J Exp Biol 2008
:
Hyperthermia induced
p38-MAPK activation was found to be dependent on the Na+/H+ exchanger 1 (NHE1) and was also
suppressed by catalase (Cat) and
superoxide dismutase ( SOD ) , implicating the generation of reactive oxygen species ( ROS )
Obara et al., Biol Pharm Bull 2011
:
Further, we determined the
involvement of
p38-mitogen activated protein kinase ( p38-MAPK ) in the reduction of
EC-SOD