Gene interactions and pathways from curated databases and text-mining

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IL2RA — IRF6

Text-mined interactions from Literome

Mehlhop et al., J Immunol Methods 2002 (Simian Acquired Immunodeficiency Syndrome) : In general, macaque DCs exhibited weaker responses to LPS and Poly I:C than human DCs, and soluble CD40L stimulation induced variable expression of CD25
Shirai et al., J Clin Immunol 2004 : Further, BV-LPS induced CD25 and Foxp3 expression in lymphocytes and CD4 ( + ) CD25 ( + ) cells expressed IL-10 mRNA ... Thus, the low expression of functioning LPS receptor molecules and induction of IL-10 producing CD4 ( + ) CD25 ( + ) lymphocytes by indigenous LPS may play a central role in the maintenance of colonic immunological homeostasis
Scheibenbogen et al., Res Immunol 1992 : Lipopolysaccharide (LPS) upregulates expression of p75 and effectively induces surface expression of CD25 on human monocytes within 18 h, as detected by two-colour FACS analysis on 59.5 +/- 7.6 % of cells
Kaya et al., Immunology 2005 : We further demonstrate that LPS induced marked up-regulation of CD25 and CD69 on T cells from CR1/CR2 sufficient (Cr+/+), but significantly lower up-regulation on T cells from CR1/CR2 deficient (Cr-/-) mice
Mnasria et al., J Leukoc Biol 2008 : In this study, we confirm that the stimulation of human monocyte derived DC with LPS strongly induced the expression of CD25 and that LPS matured DC also expressed the beta and gamma chain of the IL-2R
Milkova et al., Exp Dermatol 2010 : We demonstrated that LPS in combination with IL-2 induces human CD25 ( + ) FoxP3 ( + ) T cells in vitro
Weng et al., Int Immunol 1997 : The first pattern, characterized by the responses of all T cells, HLA-DRlo cells, monocytes, IL-2R+ cells, IFN-gamma, and augmented lymphocyte mitotic responses to lipopolysaccharide (LPS) and SEB in culture, was a rapid increase at 20 min followed by a quick decrease at 90 min to approximately the original levels