Hwang et al., Cancer Lett 2007
(Colonic Neoplasms) :
These findings support the regulatory role of AMPK in COX-2 expression in EGCG treated cancer cells
Lee et al., J Agric Food Chem 2009
(Breast Neoplasms) :
Stimulation of AMPK by curcumin resulted in the down-regulation of PPAR ( peroxisome proliferator activated receptor ) -gamma in 3T3-L1 adipocytes and the decrease in COX-2 in MCF-7 cells
Shin et al., BMB Rep 2010
:
Transduced PEP-1-AMPK inhibits the LPS induced expression of COX-2 and iNOS in Raw264.7 cells
Han et al., J Am Soc Nephrol 2011
(Dehydration) :
Activation of AMPK markedly increased hypertonicity induced apoptosis of RMICs and suppressed both hypertonicity induced NF?B nuclear translocation and cyclooxygenase-2 (COX-2) activation ; overexpression of COX-2 significantly attenuated these effects