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ANG — HNRNPK
Text-mined interactions from Literome
Feliers et al., American journal of physiology. Renal physiology 2007
:
ANG II
increased hnRNP K binding to VEGF mRNA at the same time as it stimulated its translation, suggesting that hnRNP K contributes to VEGF mRNA translation ... Inhibition of
hnRNP K expression by RNA interference significantly
reduced ANG II stimulation of VEGF synthesis ...
ANG II
increased hnRNP K phosphorylation on both tyrosine and serine residues with distinct time courses ; only Ser302 phosphorylation paralleled binding to VEGF mRNA
Sataranatarajan et al., Cell Signal 2008
(Diabetes Mellitus, Type 2...) :
In the signaling pathway leading to
hnRNP K activation
induced by
Ang II, PKCdelta is downstream of c-src ... PKCdelta mediated phosphorylation of
hnRNP K is
required for
Ang II stimulation of VEGF mRNA translation