Blumenthal et al., Clin Genet 2002
(Obesity) :
Given the stimulatory effect of NPY on adipocyte lipoprotein lipase (LPL) activity, and the lack of association of other polymorphisms with serum lipid levels, we hypothesize that this is a gain-in-function polymorphism
Elitsur et al., Neuropeptides 1994
:
Moreover, exogenous IL1-beta partially restored NPY 's stimulatory effect on monocyte depleted LPL DNA synthesis
Zarjevski et al., Endocrinology 1993
(Obesity) :
Under the ad libitum and pair feeding conditions, icv NPY stimulated glucose uptake as well as total lipoprotein lipase activity in white adipose tissue ; it resulted in an increase total activity of hepatic and white adipose tissue acetyl coenzyme-A-carboxylase