Gene interactions and pathways from curated databases and text-mining

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BRD8 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Gerona-Navarro et al., J Am Chem Soc 2011 : Our results strongly argue that these CBP modulators can effectively inhibit p53 transcriptional activity by blocking p53K382ac binding to CBP BRD and promoting p53 instability by changes of its post-translational modification states, a different mechanism than that of the p53 inhibitors reported to date
Blagosklonny et al., Biochem Biophys Res Commun 1998 : However, induction of p120 was independent of p53 ; and expression of exogenous wt p53 induced p21WAF1/CIP1 but not p120, excluding p120 as a transcriptional target of p53