Gene interactions and pathways from curated databases and text-mining

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IL10 — IRAK4

Text-mined interactions from Literome

da Silva et al., J Infect Dis 1999 (HIV Infections) : Compared with the control subjects, the HIV infected subjects had a significantly reduced IL-10 response and a reduced IL-1 receptor antagonist response
Carl et al., J Leukoc Biol 2004 : Role of endogenous IL-10 in LPS induced STAT3 activation and IL-1 receptor antagonist gene expression
Kim et al., J Biol Chem 2005 (Inflammation) : Importantly, endogenous mPLK/IRAK was activated in response to TNF-alpha or interleukin 1 treatment of primary adipose cells
Schreiber et al., Gastroenterology 1995 (Inflammatory Bowel Diseases) : In parallel, IL-1 receptor antagonist secretion is induced, and IL-10 can restore diminished in vitro IL-1 receptor antagonist/IL-1 beta ratios in IBD to normal levels
Cassatella et al., J Exp Med 1994 : Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide stimulated human polymorphonuclear leukocytes by delaying mRNA degradation