◀ Back to BMP1
BMP1 — FGFR3
Text-mined interactions from Literome
Chaki et al., Res Commun Chem Pathol Pharmacol 1990
:
NMDA evoked [ 3H ]
ACh release from the rat hippocampal slices was effectively
inhibited by
PCP
Snell et al., Life Sci 1987
:
The
effects of
PCP and metaphit, alone or in combination, on NMDA induced
ACh release were paralleled by a loss of 3H-TCP binding sites in striatal tissue incubated under identical conditions suggesting that metaphit exerts long lasting agonist-like actions on PCP receptors coupled to NMDA receptors
Jones et al., Neuropharmacology 1987
:
Phencyclidine ( 0.1 microM ) also significantly inhibited kainic acid and quisqualic acid induced release of ACh in magnesium-free but not magnesium containing buffer, suggesting that the
effect of
PCP on kainic acid- and possibly quisqualic acid stimulated release of
ACh is on that part of the response which is mediated by NMDA receptors
Leventer et al., Life Sci 1984
:
Given that PCP has been shown to stimulate basal DA release in this preparation, it is possible that
PCP , EKC and ( + ) SKF10047
inhibit ACh release indirectly by stimulating DA release
Leventer et al., J Pharmacol Exp Ther 1983
:
Therefore, we have studied the
effects of
PCP on
ACh release from rat striatal slices in order to characterize the effect of PCP in a central cholinergic system ... The presence of
PCP led to dose related inhibition of K+-stimulated
ACh release ... Haloperidol blocked the inhibitory
effects of
PCP , amphetamine and pergolide on
ACh release, supporting the notion that the decrease in ACh release produced by PCP is mediated indirectly via the release of dopamine onto cholinergic neurons