◀ Back to IGF2
EIF4EBP1 — IGF2
Text-mined interactions from Literome
Sneddon et al., Am J Physiol Endocrinol Metab 2001
:
These novel findings indicate that clenbuterol induced muscle anabolism is potentially mediated, at least in part, by an
IGF-II induced activation of
4E-BP1 and p70 ( S6k )
Cao et al., Science signaling 2009
:
Loss of Galpha ( i1 ) and Galpha ( i3 ) severely impaired the activation of Akt and of p70 S6 kinase and
4E-BP1 , downstream targets of mTORC1, in
response to EGF, heparin binding EGF-like growth factor, and transforming growth factor alpha, but not insulin,
insulin-like growth factor , or platelet derived growth factor
Xu et al., J Biol Chem 1998
:
In addition, we find that amino acids are necessary for
insulin-like growth factor ( IGF-I ) to
stimulate the phosphorylation of
PHAS-I indicating that a requirement for amino acids may be essential for other beta-cell growth factors in addition to insulin and IGF-I to activate this signaling pathway