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APOB — DDAH1

Text-mined interactions from Literome

Ito et al., Circulation 1999 (Hypercholesterolemia) : Accordingly, we studied the effects of oxidized LDL ( oxLDL ) or tumor necrosis factor-alpha (TNF-alpha) on the accumulation of ADMA by transformed human umbilical vein endothelial cells ( ECV304 ) and on the enzyme dimethylarginine dimethylaminohydrolase ( DDAH ), which degrades ADMA
Jiang et al., Acta Pharmacol Sin 2004 : In cultured ECV304 cells, LDL or ox-LDL markedly increased the level of ADMA and TNF-alpha and potentiated the adhesion of monocytes to endothelial cells, concomitantly with a significantly decrease in the activity of DDAH and serum level of NO
Jiang et al., J Ethnopharmacol 2004 : DMB also significantly reduced the decreased activity of dimethylarginine dimethylaminohydrolase ( DDAH ) induced by LDL in cultured endothelial cells
Xie et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 : Pretreatment with losartan ( 10 ( -8 ) - 10 ( -6 ) mmol/L ) significantly inhibited the increased levels of ADMA, LDH and TNF-alpha, attenuated the decreased levels of NO and the decreased activity of DDAH induced by ox-LDL ( P < 0.05 )
Tan et al., Vascul Pharmacol 2007 : Taurine ( 1 or 5 microg/ml ) significantly attenuated the increases in the levels of LDH, ADMA, TNF-alpha and MDA, and the decrease in the level of NO and the activity of DDAH induced by ox-LDL in HUVECs