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ARSK — TRAF6
Text-mined interactions from Literome
Noguchi et al., J Biol Chem 2005
:
Consistent with our previous findings that TRAF2 and
TRAF6 activate ASK1, H ( 2 ) O ( 2 ) -induced
ASK1 activation and cell death were strongly reduced in the cells derived from Traf2-/- and Traf6-/- mice
Fujino et al., Mol Cell Biol 2007
:
However, the precise mechanisms by which Trx inhibits and TRAF2 and
TRAF6 activate
ASK1 have not been elucidated fully ... These findings demonstrate that Trx,
TRAF2 , and TRAF6
regulate ASK1 activity by modulating N-terminal homophilic interaction of ASK1
Yuk et al., Immunol Cell Biol 2009
(Tuberculosis) :
Furthermore, we present evidence that TNF receptor associated factor
(TRAF) 6 activities were
essential for ROS mediated
ASK1 activation by M. bovis BCG
Nishitoh et al., Mol Cell 1998
:
Here we show that
ASK1 interacts with members of the TRAF family and is
activated by TRAF2, TRAF5, and
TRAF6 overexpression