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LRPPRC — STAT1

Text-mined interactions from Literome

Jenkins et al., Exp Hematol 2002 (Thrombocytopenia) : Hematopoiesis was examined at various developmental stages in mice homozygous for a targeted carboxy-terminal truncation mutation in gp130 ( gp130 ( delta ) / ( delta ) ) that deletes all STAT1/3 binding sites, thereby abolishing gp130 mediated STAT1/3 activation
Jenkins et al., Mol Cell Biol 2004 (MAP Kinase Signaling System) : Here we have utilized macrophages devoid of either gp130 dependent STAT1/3 ( gp130 ( Delta STAT/Delta STAT ) ) or extracellular signal regulated kinases 1 and 2 ( ERK1/2 ) mitogen activated protein ( MAP ) kinase ( gp130 ( Y757F/Y757F ) ) activation to assess the individual contribution of each pathway to macrophage formation
Klein et al., J Clin Invest 2005 (Hepatitis) : This was demonstrated by analysis of IL-6 induced protection in mice selectively deficient for gp130 dependent STAT1/3 or gp130-SHP2-RAS signaling in hepatocytes