Gene interactions and pathways from curated databases and text-mining

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BDNF — CEP72

Text-mined interactions from Literome

Evans et al., Med Pediatr Oncol 2001 (Neuroblastoma) : The effect of CEP-751 on TrkB activation by BDNF was examined in G12 cells in culture by immunoprecipitation with antipan Trk antiserum, followed by Western blot analysis using antiphosphotyrosine antibodies ... Activation of TrkB by BDNF in G12 cells was inhibited by CEP-751 in a dose dependent fashion
Apostol et al., Mol Cell Neurosci 2008 (Disease Models, Animal...) : CEP-1347 reduces mutant huntingtin associated neurotoxicity and restores BDNF levels in R6/2 mice ... Finally, CEP-1347 improved motor performance in R6/2 mice and restored expression of BDNF , a critical neurotrophic factor that is reduced in HD