We have a suspicion that you are an automated web bot software, not a real user.
To keep our site fast for other users, we have slowed down this page.
The slowdown will gradually disappear.
If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu.
Also note that all data for hgGeneGraph can be obtained through our public MySQL server and
all our software source code is available and can be installed locally onto your own computer.
If you are unsure how to use these resources, do not hesitate to contact us.
Kim et al., Cancer Res 2004
(Breast Neoplasms) :
Induction of IGFBP-3 using an ecdysone-inducible expression system inhibited DNA synthesis in an IGF-IGF receptor axis independent fashion and resulted in the subsequent induction of apoptosis and an increase in caspase activity
Dar et al., J Invest Dermatol 2010
(Melanoma...) :
IGFBP3 overexpression also resulted in cleavage of caspase 3 and reduced expression of phosphorylated AKT