Gene interactions and pathways from curated databases and text-mining

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FGFR3 — JAK2

Text-mined interactions from Literome

Zecchin et al., Diabetes 2007 (Obesity) : In the present study, we show that ACh induces rapid tyrosine phosphorylation and activation of Janus kinase 2 (JAK2) in rat aorta ... In addition, ACh induces JAK2/IRS-1 and IRS-1/phosphatidylinositol (PI) 3-kinase associations, downstream activation of Akt/protein kinase B, endothelial cell-nitric oxide synthase ( eNOS ), and extracellular signal regulated kinase ( ERK ) -1/2
Scuto et al., Leukemia 2011 (MAP Kinase Signaling System...) : The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival