◀ Back to JAK2
FGFR3 — JAK2
Text-mined interactions from Literome
Zecchin et al., Diabetes 2007
(Obesity) :
In the present study, we show that
ACh induces rapid tyrosine phosphorylation and activation of
Janus kinase 2 (JAK2) in rat aorta ... In addition,
ACh induces
JAK2/IRS-1 and IRS-1/phosphatidylinositol (PI) 3-kinase associations, downstream activation of Akt/protein kinase B, endothelial cell-nitric oxide synthase ( eNOS ), and extracellular signal regulated kinase ( ERK ) -1/2
Scuto et al., Leukemia 2011
(MAP Kinase Signaling System...) :
The novel
JAK inhibitor AZD1480
blocks STAT3 and
FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival