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FOXO3 — NOS3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: NOS3 → FOXO3 (directlyDecreases, NOS3 Activity) Potente et al., J Clin Invest 2005*
  Evidence: Whereas angiopoietin 2 (Ang2) was exclusively regulated by Foxo1, eNOS, which is essential for postnatal neovascularization, was regulated by Foxo1 and Foxo3a. Consistent with these findings, constitutively active Foxo1 and Foxo3a repressed eNOS protein expression and bound to the eNOS promoter.

Text-mined interactions from Literome

Potente et al., J Clin Invest 2005 (Ischemia) : Consistent with these findings, constitutively active Foxo1 and Foxo3a repressed eNOS protein expression and bound to the eNOS promoter ... In vivo, Foxo3a deficiency increased eNOS expression and enhanced postnatal vessel formation and maturation
Alhosin et al., PloS one 2013 : Redox-Sensitive Up-Regulation of eNOS by Purple Grape Juice in Endothelial Cells : Role of PI3-Kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a