Blázquez et al., Cancer Res 2008
(Glioblastoma...) :
Local administration of Delta ( 9 ) -tetrahydrocannabinol (THC) , the major active ingredient of cannabis, down-regulated MMP-2 expression in gliomas generated in mice, as determined by Western blot, immunofluorescence, and real-time quantitative PCR analyses ... THC inhibited MMP-2 expression and cell invasion in cultured glioma cells
Yodkeeree et al., Acta Pharmacol Sin 2008
(Neoplasm Invasiveness) :
Zymography assay was used to analyze the effect of THC on matrix metalloproteinase (MMP)-2 , MMP-9, and urokinase plasminogen activator (uPA) secretion from HT1080 cells