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CD46 — INS
Text-mined interactions from Literome
Sell et al., Endocrinology 2006
(Inflammation) :
Among these candidates,
MCP-1 alone
impaired insulin signaling in skeletal muscle cells at doses similar to its physiological plasma concentrations ( 200 pg/ml ), whereas IL-6, IL-8, and macrophage inflammatory protein-1beta were effective at very high concentrations only
Bennett et al., Diabetes 1997
:
Insulin , the primary substrate for IDE,
inhibits the proteolytic activity of the
IDE-MCP complex but not of purified MCP
Hamel et al., Endocrinology 1998
:
Inhibitors of IDE also blocked the
insulin effect on
MCP activity, as did treatment with SDS