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MST1 — NOS2

Text-mined interactions from Literome

Morrison et al., J Immunol 2002 : Our lab and others have previously shown that macrophage stimulating protein (MSP) , through activation of its receptor RON, negatively regulates NO production in response to IFN-gamma and LPS by inhibiting the expression of inducible NO synthase (iNOS)
Lee et al., Biochem Biophys Res Commun 2013 (Inflammation) : GM reduced expression of anti-apoptotic protein Bcl-2 and induced expression of Bax and cleaved caspase 3 ; these effects and GM-induced expression of COX-2 and iNOS were also attenuated by MSP
Chen et al., J Immunol 1998 (Inflammation) : Activation of RON by MSP in mature exudate macrophages inhibits LPS- and IFN-gamma induced iNOS synthesis