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ATF2 — IFNG

Pathways - manually collected, often from reviews:

• BioCarta the 41bb-dependent immune response: IFN-gamma (IFNG) → ATF-2 (ATF2) (transcription, collaborate)
• NCI Pathway Database ATF-2 transcription factor network: JUN/ATF2 complex (JUN-ATF2) → IFN-gamma (IFNG) (transcription, activates) Penix et al., J Biol Chem 1996*
  Evidence: assay, physical interaction

Text-mined interactions from Literome

Zhang et al., J Immunol 1999 : T cell proliferation and production of IL-2, IL-4, and IFN-gamma induced by both CD3 and CD3/CD28 ligation and the nuclear expression of the c-Jun and ATF-2 proteins are each blocked by the p38 MAPK inhibitor SB203580
Nakayama et al., Nucleic acids research. Supplement (2001) 2001 : Thus, these results indicate that p300 and ATF-2 play critical rules in a basal transcription of IFN gamma gene in Jurkat T cells
Kimura et al., Am J Pathol 2006 (Acute Kidney Injury) : In contrast, the absence of IFN-gamma augmented transforming growth factor-beta-Smad3 signal pathway and eventually enhanced the expression of activating transcription factor 3, which is presumed to repress Nrf2 mediated MRP1 gene expression
Samten et al., J Immunol 2008 : Inhibition of ATF-2 activity in T cells with a dominant negative ATF-2 peptide or with small interfering RNA markedly reduced the expression of IFN-gamma and decreased the expression of CREB and c-Jun