Gene interactions and pathways from curated databases and text-mining

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MET — NTRK1

Text-mined interactions from Literome

Shen et al., Bioorg Med Chem 2005 : Geldanamycin derivative inhibition of HGF/SF mediated Met tyrosine kinase receptor dependent urokinase-plasminogen activation ... We have found that geldanamycin and some of its derivatives can inhibit hepatocyte growth factor/scatter factor mediated Met tyrosine kinase receptor dependent urokinase-plasminogen activation at femtomolar levels
Labbé et al., J Nutr 2009 (Medulloblastoma) : Interestingly, the inhibitory effects of quercetin on the tyrosine kinase receptor Met [ half-maximal inhibitory effect ( IC ( 50 ) ) of 12 micromol/L ] or on the Met induced activation of Akt ( IC ( 50 ) of 2.5 micromol/L ) occurred at concentrations achievable through dietary approaches