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MMP1 — RAC1

Text-mined interactions from Literome

Westermarck et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : In contrast, activation of stress activated c-Jun N-terminal kinase and p38 pathways by expression of constitutively active mutants of Rac , transforming growth factor beta activated kinase 1 ( TAK1 ), MAPK kinase 3 ( MKK3 ), or MKK6 or by treatment with arsenite or anisomycin did not alone markedly enhance MMP-1 promoter activity
Zhuge et al., J Biol Chem 2001 (Carcinoma, Squamous Cell...) : The Rac1 dependent MMP-2 activation occurred in a cell associated fashion and required MMP activities
Stallings-Mann et al., Sci Transl Med 2012 (Adenocarcinoma...) : We show that expression of mouse Rac1b in lung epithelial cells of transgenic mice stimulated EMT and spontaneous tumor development and that activation of EMT by MMP induced expression of Rac1b gave rise to lung adenocarcinoma in the transgenic mice through bypassing oncogene induced senescence
Serratì et al., Arthritis Rheum 2013 (Scleroderma, Systemic) : Motility increase required Rac1 activation and RhoA inhibition and was inhibited by an MMP inhibitor
Newberry et al., Mol Endocrinol 1997 : Dominant negative Ras abrogates MMP1 induction by constitutively active FGFR2-ROS, but dominant negative Rho and Rac do not inhibit induction