Gene interactions and pathways from curated databases and text-mining

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ADRA1B — IGF1

Text-mined interactions from Literome

Molina-Muñoz et al., Mol Endocrinol 2006 : IGF-I induces alpha(1B)-adrenoceptor ( alpha ( 1B ) -AR ) phosphorylation
Molina-Muñoz et al., Eur J Pharmacol 2008 : IGF-I induced alpha(1B)-adrenoceptor phosphorylation, which was markedly reduced by the following agents : pertussis toxin, a metalloproteinase inhibitor, diphtheria toxin mutant CRM 197, an epidermal growth factor (EGF) receptor intrinsic kinase activity inhibitor, and by phosphoinositide 3-kinase and protein kinase C inhibitors ... Our data show that IGF-I induces alpha(1B)-adrenoceptor desensitization associated to receptor phosphorylation and internalization