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CDH5 — IL8

Text-mined interactions from Literome

Sears et al., Infect Immun 2006 : Determination of BFT activity on HT29/C1 cells, cleavage of E-cadherin , and the capacity to induce interleukin-8 secretion by wild-type BFT and C-terminal deletion mutants showed that deletion of only 2 amino acid residues at the C terminus significantly reduced BFT biological activity and deletion of eight or more amino acid residues obliterated BFT biologic activity
Gavard et al., Mol Cell Biol 2009 : Here, we show that in endothelial cells IL-8 initiates a signaling route that converges with that deployed by VEGF at the level of the small GTPase Rac1 and that both act through the p21 activated kinase to promote the phosphorylation and internalization of VE-cadherin