Gene interactions and pathways from curated databases and text-mining

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CA2 — CD28

Text-mined interactions from Literome

Kim et al., J Biol Chem 2009 (Calcium Signaling) : Using membrane vesicles expressing the mouse class I major histocompatibility complex, i.e. Ld plus costimulatory ligands, i.e. B7-1 and intercellular adhesion molecule-1 along with 2C T cell receptor transgenic T cells, we investigated the roles of CD28 and LFA-1 ( lymphocyte function associated antigen-1 ) in the activation of PLC-gamma1 and Ca2+ signaling
Vandenberghe et al., Immunology 1993 : Cross linking of CD5 or CD28 induces an early rise of cytoplasmic free calcium concentration ( [ Ca2+ ) ] i ) and both this rise and CD69 expression were inhibited by chelation of extracellular Ca2+ with ethyleneglycol-bis- ( 2-aminoethyl ) -tetraacetate ( EGTA )