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CA2 — GPR125
Text-mined interactions from Literome
Olszewska-Pazdrak et al., J Biol Chem 2004
:
G17 activation of the cholecystokinin/gastrin receptor ( CCK ( 2 ) R ), a
G protein coupled receptor ,
stimulates release of
Ca2+ from inositol 1,4,5-triphosphate-sensitive Ca2+ stores
Feisst et al., Mol Pharmacol 2005
:
In human polymorphonuclear leukocytes ( PMNLs ), U-73122 inhibited increases in
[Ca2+ ] i
induced by
G protein coupled receptor ( GPCR ) agonists ( N-formyl-methionyl-leucyl-phenylalanine or platelet activating factor ; IC50 of approximately 2 to 4 microM ), but it failed to suppress responses induced by ionomycin or thapsigargin
Fan et al., J Biol Chem 2005
:
Thus, our results demonstrate that
G protein coupled receptor activation
induces rapid FAK phosphorylation at Ser-843 through
Ca2+ , calmodulin, and CaMKII
Kubota et al., J Neurosci 2006
:
Furthermore,
G-protein coupled receptor mediated
[Ca2+ ] i increase was attenuated in hippocampal neurons of the mutant mice
Denning et al., Am J Physiol 1998
:
At lower concentrations, pyocyanine inhibits inositol 1,4,5-trisphosphate formation and [
Ca2+ ] c increases in
response to
G protein coupled receptor agonists