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ESR1 — SERPINE1

Text-mined interactions from Literome

Smith et al., Circ Res 2004 : ERalpha increased PAI-1 promoter activity in BAECs by an estrogen dependent mechanism, whereas ERbeta suppressed PAI-1 promoter activity by an estrogen independent mechanism ... ERalpha activated the PAI-1 promoter through a proximal ERE ( -427 ) and possibly additional EREs located within the PAI-1 promoter, whereas ERbeta suppressed the promoter construct via an unidentified mechanism
Stope et al., Breast Cancer Res Treat 2010 (Breast Neoplasms) : Our results indicate a permanent repression of PAI-1 by ERalpha and suggest a ligand independent crosstalk between ERalpha and TGF-beta signaling in breast cancer cells