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CCK — LEP

Text-mined interactions from Literome

Brzozowski et al., Eur J Pharmacol 1999 : CCK ( 1-100 microg/kg i.p. ), given in graded doses, produced a dose dependent increase in the plasma leptin level and a rise of the expression of ob messenger RNA ( mRNA ) in gastric mucosa, the maximum being reached at a dose of 100 microg/kg
Attoub et al., Endocrinology 1999 : Physiological role of cholecystokinin B/gastrin receptor in leptin secretion ... These data argue for a physiological role for the CCK-B/gastrin receptor in adipocyte leptin regulation
Buyse et al., Eur J Neurosci 2001 : Recent studies have shown a synergistic interaction between leptin and cholecystokinin (CCK) leading to suppression of food intake, which involves CCK-1 receptors and capsaicin-sensitive vagal fibres
Konturek et al., Scand J Gastroenterol 2001 (Helicobacter Infections) : 1 ) The gastric meal and CCK enhance the release of leptin in H. pylori positive patients and this leptin is capable of inhibiting basal and meal stimulated gastric H+ secretion, while raising plasma gastrin and reducing the plasma CCK levels, and 2 ) the eradication of H. pylori reduces the postprandial gastric H+ and plasmagastrin responses as well as the release of leptin in response to CCK and meal
Brzozowski et al., J Physiol Pharmacol 2001 (Reperfusion Injury) : This protective effect of leptin was accompanied by a significant increase in GBF and plasma gastrin levels whereas CCK-8 increased plasma leptin levels but failed to affect plasma gastrin levels
Guilmeau et al., Eur J Pharmacol 2002 : Furthermore, intraperitoneal leptin induced a rapid increase in plasma CCK levels in vivo in the rat
Volkoff et al., Brain Res 2003 : Role of leptin in the control of feeding of goldfish Carassius auratus : interactions with cholecystokinin , neuropeptide Y and orexin A, and modulation by fasting
Tsunoda et al., Biochem Biophys Res Commun 2003 : The objective of this study was to demonstrate if CCK enhances leptin synthesis and secretion in isolated canine gastric chief cells ... These results indicate that canine chief cells synthesize and secrete leptin in response to CCK via the high-affinity state of the CCK-A receptor
Blevins et al., Am J Physiol Regul Integr Comp Physiol 2004 : OVT resulted in a significant 37 % decrease ( P < 0.05 ) in the potentiating effect of leptin on CCK activation of mNTS neuronal Fos expression
Kiely et al., J Surg Res 2005 (Obesity) : Leptin deficiency resulted in increased jejunal responses to CCK ( P < 0.05 ) and a similar response to ACh compared to lean controls
Kiely et al., J Surg Res 2005 (Obesity) : Leptin increases duodenal secretion of cholecystokinin (CCK) and acts with CCK on vagal mechanoreceptors in the regulation of small intestinal motility
Volkoff et al., Gen Comp Endocrinol 2005 : Moreover, leptin induces CCK gene expression in the hypothalamus and its actions are mediated at least in part by CCK
Milke García et al., Rev Gastroenterol Mex 2005 : Satiation biomarkers ( stop feeding ) are gastric distention and hormones ( CCK , GLP-1 ) and satiety biomarkers ( induce feeding ) are food induced thermogenesis, body temperature, glycaemia and also hormones ( insulin, leptin and ghrelin )
Wang et al., Zhonghua Yi Xue Za Zhi 2006 : The effect of leptin on gastric motility is mediated by cholinergic nerve and CCK-A receptors
Williams et al., J Histochem Cytochem 2008 : Here, neither le0ptin nor CCK alone affected the relative amount of mRNA in the TH cell enriched samples, but leptin plus CCK substantially increased c-Fos mRNA content
Maletínská et al., BMC neuroscience 2008 (Thinness) : This study is based on previously found synergistic effect of leptin and CCK on food intake and our hypothesis on a co-operation of the CART peptide and CCK in food intake regulation and Fos activation in their common targets, the nucleus tractus solitarii of the brainstem ( NTS ), the paraventricular nucleus ( PVN ), and the dorsomedial nucleus ( DMH ) of the hypothalamus
Köhnke et al., Scand J Gastroenterol 2009 : The CCK level increased, in particular between the 120 min time-point and onwards, the ghrelin level was reduced at 120 min and leptin level increased at 360 min after intake of the thylakoid enriched meal
Li et al., Am J Physiol Gastrointest Liver Physiol 2011 : Research has shown that leptin , in the presence of CCK , may mediate the control of short-term food intake
de Lartigue et al., PloS one 2012 (Body Weight...) : Leptin enhances CCK signaling in VAN via an early growth response 1 (EGR1) dependent pathway thereby increasing their sensitivity to CCK ... Leptin signaling in VAN is required for appropriate CCK signaling and satiation
Woods et al., Am J Physiol Endocrinol Metab 2012 : For example, cholecystokinin (CCK) , a duodenal peptide secreted during meals that aids in digestion, also reduces ongoing food intake, thereby contributing to satiation ; and insulin and leptin , hormones secreted in direct proportion to body fat, act in the brain to help control adiposity by reducing energy intake
Barrachina et al., Proc Natl Acad Sci U S A 1997 : These results indicate the existence of a functional synergistic interaction between leptin and CCK leading to early suppression of food intake which involves CCK-A receptors and capsaicin-sensitive afferent fibers