◀ Back to MMP1
KDR — MMP1
Text-mined interactions from Literome
Sato et al., Ann N Y Acad Sci 2000
:
The KDR/Flt-1 heterodimer and the
KDR homodimer
mediate the expression of Ets-1,
MMP-1 , and Flt-1
Adya et al., Cardiovasc Res 2008
:
Inhibition of
VEGFR2 and VEGF [ by soluble FMS-like tyrosine kinase-1 ( sFlt1 ) ]
down-regulated visfatin induced
MMP induction
Abdul Muneer et al., Arterioscler Thromb Vasc Biol 2012
(Disease Models, Animal...) :
The mechanisms of cerebral vascular dysfunction and neuroinflammation by
MMP mediated degradation of
VEGFR-2 in alcohol ingestion
Mazor et al., J Biol Chem 2013
:
Although MMP-1 and VEGFR2 co-exist in many normal and pathophysiological conditions, the
effect of
MMP-1 on cellular
VEGFR2 that can promote the above processes is unknown
dela Paz et al., Biochem Biophys Res Commun 2013
:
Early
VEGFR2 activation in response to flow is VEGF dependent and
mediated by
MMP activity ... Finally, we show that flow induced
VEGFR2 activation is attenuated in the
presence of the broad spectrum
matrix metalloproteinase ( MMP ) inhibitor, GM6001