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BCL6 — EGF
Text-mined interactions from Literome
Cui et al., Mol Reprod Dev 2003
:
Furthermore, semi-quantitative reverse transcriptase-polymerase chain reaction ( RT-PCR ) revealed that
EGF enhanced the mRNA expression of
Bcl-xL in the presence of 0.4 % BSA but BSA and EGF alone had no effect ... These results suggest that
EGF and BSA synergistically
enhance Bcl-xL gene expression, which may result in a net increase in cell number in porcine presumptive diploid parthenotes developing in vitro
Jin et al., J Cell Physiol 2007
:
Epidermal growth factor (EGF) induces Bad phosphorylation at Ser112 via mitogen activated protein kinase ( MAPK ), impairing its binding to Bcl-2 and
Bcl-xL and interfering with their anti-apoptotic functions
Hirata et al., Br J Cancer 2009
(Neoplasm Invasiveness...) :
The
HB-EGF-CTF nuclear translocation
leads to the interaction of
BCL6 with HB-EGF-CTF and the nuclear export of BCL6, and after that BCL6 degradation was mediated by ubiquitin/proteasome pathway