Gene interactions and pathways from curated databases and text-mining

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EMD — TNFRSF11B

Text-mined interactions from Literome

He et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004 : The purpose of this study was to investigate the effects of EMD on the growth and differentiation of osteoblastic cells ( MC3T3-E1 ) and on the expression of osteoprotegerin (OPG) , a key cytokine that inhibits osteoclastogenesis and osteoclast function
Lossdörfer et al., J Dent Res 2007 : These results suggest that EMD promotes periodontal ligament cell differentiation and osteoprotegerin production, potentially resulting in a microenvironment supporting periodontal repair, whereas combining EMD and PTH ( 1-34 ) failed to prove beneficial in this respect
Qu et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 : Finally, EMD enhanced mRNA expression level of OPG and did not influence that of RANKL