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APOE — TNF

Text-mined interactions from Literome

Starck et al., Cell Biochem Funct 2000 (Astrocytoma) : After 48 h of incubation, apoE secretion was inhibited by TNF-alpha but not affected by IL-1beta and IFN-gamma
Zechner et al., J Biol Chem 1991 : Human recombinant tumor necrosis factor , a potent inhibitor of LPL gene transcription, had no effect on adipocyte apoE mRNA levels
Yue et al., Endocrinology 2008 : Tumor necrosis factor-alpha mediated suppression of adipocyte apolipoprotein E gene transcription : primary role for the nuclear factor (NF)-kappaB pathway and NFkappaB p50 ... We have previously reported that TNFalpha reduces adipocyte apoE , and the current studies were undertaken to evaluate the molecular mechanism for this regulation ... Reduction of p50 expression using small interference RNA completely eliminated TNFalpha mediated reduction of endogenous adipocyte apoE gene expression
Wei et al., Neurobiol Dis 2013 : We observed that the absence of apoE resulted in the increased proportion of Th1 and Th17 cells in the spleens and brains, as well as up-regulated expressions of proinflammatory cytokines ( IL-17, IFN-?, TNF-a , IL-12, IL-1ß and IL-6 ) and transcription factors ( ROR?t and T-bet ) in the CNS
Laskowitz et al., J Neuroimmunol 1997 : Apolipoprotein E suppresses glial cell secretion of TNF alpha ... We prepared mixed neuronal-glial cultures from apoE deficient mouse pups and measured secretion of TNF alpha after stimulation with lipopolysaccharide (LPS) in the presence and absence of human recombinant apoE3 and E4
Song et al., Cytokine 1998 : IL-1 beta and TNF-alpha suppress apolipoprotein ( apo ) E secretion and apo A-I expression in HepG2 cells