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MAPK14 — SMN1
Text-mined interactions from Literome
Shen et al., Biochem Biophys Res Commun 2006
:
Inhibiting
p38MAPK with SB202190 or JNK with SP600125 also
reduced angiotensin II-induced
alpha-SMA expression
Vepachedu et al., J Immunol 2007
(MAP Kinase Signaling System...) :
Blocking p38
MAPK resulted in reduced
alpha-SMA expression by Unc119 suggesting that the p38 pathway regulates Unc119 induced myofibroblast differentiation
Ding et al., J Biol Chem 2008
(Disease Models, Animal...) :
Although both ERK and p38
MAPK activation is
required for maximal TGF-beta1 induced
alpha-SMA expression, ERK is the major signaling intermediate in cells that express FAK
Pappas et al., Eur J Vasc Endovasc Surg 2009
(Chronic Disease...) :
alpha-SMA protein expression in LC fibroblasts
increased with
MAPK inhibition with/without TGF-beta(1) stimulation, and correlated with the degree of gel contraction
Liu et al., Nan Fang Yi Ke Da Xue Xue Bao 2011
(Scleroderma, Systemic) :
In the presence of TGF-ß ( 1 ), blocking of Smads,
ERK/MAPK , and p38MAPK pathways, but not JNK/MAPK pathway,
caused an obvious decrease in
a-SMA levels in the fibroblasts in both groups