Gene interactions and pathways from curated databases and text-mining

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MPO — NOS1

Text-mined interactions from Literome

Ledbetter et al., Am J Vet Res 2001 : Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase , and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells
Wolfárd et al., Magy Seb 2000 (Endotoxemia) : Non-selective NOS-inhibition prevented hypotension, exerted positive inotropic effect, but induced a rise in peripheral vascular resistance and a further increase in myocardial MPO activity
Kumar et al., Nitric Oxide 2005 : Inducible nitric oxide synthase expression is inhibited by myeloperoxidase
Hock et al., Immunology 2012 : This suppression was partially reversed by catalase addition ( P < 0·01 ) and largely reversed by addition of exogenous interleukin-2 ( P < 0·001 ) but was not significantly reduced by nitric oxide synthase inhibition, myeloperoxidase inhibition or addition of excess arginine
Grisham et al., J Pharmacol Exp Ther 1994 (Chronic Disease...) : We found that chronic NOS inhibition by L-NAME or AG significantly attenuated the peptidoglycan/polysacchride ( PG/PS ) -induced increases in macroscopic colonic inflammation scores and colonic MPO activity