Gene interactions and pathways from curated databases and text-mining

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ANXA6 — IL1B

Text-mined interactions from Literome

Chen et al., Proc Natl Acad Sci U S A 2006 (Aortic Diseases...) : PDGF/IL-1beta costimulation also induced a sustained phosphorylation of Akt and p70 ribosomal S6 kinase (p70S6K) ... The effects of PDGF/IL-1beta costimulation on contractile marker expression and Akt and p70S6K phosphorylation were blocked by the phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 and by adenovirus expressing a dominant negative Akt, and they were mimicked by constitutively active Akt
Mpiga et al., Scand J Immunol 2006 (Chlamydia Infections) : When infected HeLa cells were co-cultured with THP-1 cells, IL-6 and IL-8 secretion was sustained, IL-1beta expression followed a bell shaped curve and IL-10, IL-12p70 and TNF-alpha synthesis was down regulated
Grzelkowska-Kowalczyk et al., Cell Mol Biol Lett 2010 : The aim of this study was to compare the effects of TNF-alpha, IL-1beta and IFN-gamma on the activation of protein kinase B (PKB), p70 ( S6k ), mitogen activated protein kinase ( MAPK ) and p90 ( rsk ), and on IGF-I stimulated glucose uptake and protein synthesis in mouse C2C12 myotubes