Gene interactions and pathways from curated databases and text-mining

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CCL4L2 — IL1B

Text-mined interactions from Literome

Sanchez et al., Biochem Pharmacol 2003 : Rhein partially reversed the effect of IL-1beta on TIMP-1 and NO production, had no effect on AGG, IL-6 and MIP-1beta production, but up-regulated the IL-1beta stimulated PGE ( 2 ) production
Zhang et al., Cell Immunol 2003 : Investigation of the mechanism involved in MIP-1beta induction by IL-1beta showed that IL-1beta activated the nuclear factor kappa B (NF-kappaB) promoter in Huh7 cells
Sanchez et al., Osteoarthritis Cartilage 2004 (Osteoarthritis, Knee) : At 1-10ng/ml, OSM significantly decreased IL-1beta stimulated IL-8, MIP-1beta , PGE ( 2 ) and *NO production but amplified IL-1beta stimulating effect on IL-6 production
Tseng et al., Biochem Pharmacol 2008 : Helioxanthin inhibits interleukin-1 beta induced MIP-1 beta production by reduction of c-jun expression and binding of the c-jun/CREB1 complex to the AP-1/CRE site of the MIP-1 beta promoter in Huh7 cells